产品编号：T662005

产品规格：2.5g

产品价格：面议

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产品详情

标准品编号:	T662005
名称:	(3S)-1-Tosyl-α,α-diphenyl-3-pyrrolidineacetonitrile
别名:	(S)-1-[(4-Methylphenyl)sulfonyl]-α,α-diphenyl-3-pyrrolidineacetonitrile; (S)-2,2-Diphenyl-2-(1-tosyl-3-pyrrolidinyl)acetonitrile; 2,2-Diphenyl-2-((3S)-1-tosyl-3-pyrrolidinyl)acetonitrile; (S)-2,2-Diphenyl-2-(1-tosylpyrrolidin-3-yl)acetonitrile
CAS号:	133099-09-9
分子式:	C₂₅H₂₄N₂O₂S
外观:	白色固体
熔点:	184-186°C
分子量:	416.54
储存:	-20°C Freezer
溶解度:	Chloroform, Dichloromethane
类别:	Building Blocks; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(3S)-1-Tosyl-α,α-diphenyl-3-pyrrolidineacetonitrile is a reactant used in the preparation of Darifenacin Hydrobromide (D193400), which is used as a medication to treat urinary incontinence. It works by blocking the M3 muscarinic acetylcholine receptor.
参考文献	Murthy, M.V., et. al.: J. Pharm. Biomed. Anal., 72, 40 (2013); Beaumont, K.C., et al.: Xenobiotica, 28, 63 (1998); Chapple, C.R., et al.: Expert Opin. Invest. Drugs, 13, 1493 (2004); Haab, F., et al.: Eur. Urol., 45, 420 (2004)