产品编号：V900500

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	V900500
名称:	VX 745
别名:	5-(2,6-Dichlorophenyl)-2-[(2,4-difluorophenyl)thio]-6H-pyrimido[1,6-b]pyridazin-6-one;
CAS号:	209410-46-8
分子式:	C₁₉H₉Cl₂F₂N₃OS
外观:	淡黄色固体
熔点:	259-262°C (dec.)
分子量:	436.26
储存:	-20˚C Freezer
溶解度:	Chloroform, DMSO, Methanol
类别:	Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	VX 745 is a potent and selective inhibitor of p38α mitogen-activated protein (MAP) kinase. VX 745 is a potential anti-inflammatory agents. Studies suggest that VX 745 may be useful in the treatment of Werner syndrome.
参考文献	Haddad, J.J.: Curr. Opin. Invest. Drugs, 2, 1070 (2001); Duffy, J.P. et al.: ACS Med. Chem. Lett., 2, 758 (2011); Bagley, M.C. et al.: Pharmaceuticals, 3, 1842 (2010);