URB602

我要购买

产品编号:U821925

产品规格:500mg

产品价格:面议


产品详情

标准品编号: U821925
名称: URB602
别名: Biphenyl-3-yl Carbamic Acid, Cyclohexyl Ester; N-[1,1'-Biphenyl]-3-yl-carbamic Acid Cyclohexyl Ester
CAS号: 565460-15-3
分子式: C₁₉H₂₁NO₂
外观: 白色固体
熔点: 122-123°C
分子量: 295.38
溶解度: DMSO
类别: Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;
应用: URB602 is a selective inhibitor of MGL, exhibiting an IC50 of 28 µM for the rat brain enzyme. It does not inhibit fatty acid amide hydrolase (FAAH) at concentrations up to 100 µM, or other lipid metabolizing enzymes such as diacylglycerol lipase or cyclooxygenase-2.5 6 Inhibition of 2-AG hydrolysis is associated with enhanced stress-induced analgesia and may represent a novel drug target in pain and stress management.
参考文献