产品编号：T889158

产品规格：250mg

产品价格：面议

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产品详情

标准品编号:	T889158
名称:	4-((Triphenylphosphoranylidene)amino)benzenesulfonamide
分子式:	C₂₄H₂₁N₂O₂PS
分子量:	432.47
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	4-((Triphenylphosphoranylidene)amino)benzenesulfonamide is an intermediate in the synthesis of 4-[[3-(4-Methylphenyl)-3-oxo-1-(trifluoromethyl)propylidene]amino]benzenesulfonamide (M327010), which is an impurity of Celecoxib (C251000), which is a selective cyclooxygenase-2 (COX-2) inhibitor, an anti-inflammatory agent. It is also used in treatment of familial adenomatous polyposis.
参考文献	Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998); Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000); Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000)