产品编号：T791320

产品规格：250mg

产品价格：面议

---

产品详情

标准品编号:	T791320
名称:	2-Trifluoromethyl-2'-methoxychalcone
别名:	(2E)-1-(2-Methoxyphenyl)-3-[2-(trifluoromethyl)phenyl]-2-propen-1-one;
CAS号:	1309371-03-6
分子式:	C₁₇H₁₃F₃O₂
分子量:	306.28
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	2-Trifluoromethyl-2'-methoxychalcone is a novel chalcone derivative as potent Nrf2 activators in mice and human lung epithelial cells. 2-Trifluoromethyl-2'-methoxychalcone is a potent activator of Nrf2, both, in vitro and in mice. 4 Human bronchial epithelial cells treated with 10 μM 2-trifluoromethyl-2'-methoxychalcone showed a marked increase in the expression of the Nrf2-regulated antioxidant genes, GCLM and NQO1.
参考文献	Thimmulappa, R., et al.: Cancer Res., 62, 5196 (2002); Rangasamy, T., et al.: J. Exp. Med., 202, 47 (2005); Surh, Y., et al.: Planta Med., 2008, 74, 1526 (2008); Niture, S., et al.: J. Cell Sci., 2009, 122, 4452 (2009);