产品编号：T447200

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	T447200
名称:	Tivantinib
别名:	(3R,4R)-3-(5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione; ARQ 197;
CAS号:	905854-02-6
分子式:	C₂₃H₁₉N₃O₂
外观:	Light Orange Solid
分子量:	369.42
储存:	-20°C Freezer, Under inert atmosphere
溶解度:	DMSO (Slightly), Methanol (Slightly)
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Tivantinib is a hepatocyte growth factor receptor (proto-oncogene c-Met; MET) inhibitor. Tivantinib inhibits human c-Met receptor tyrosine kinase selectively and is a promising therapeutic option for the treatment of c-Met-associated cancers. Potent c-MET inhibitor.
参考文献	Pento, J.T. et al.: Drugs Fut., 36, 893 (2011); Munshi, N. et al.: Mol. Cancer Ther., 9, 1544 (2010); Bagai, R. et al.: IDrugs, 13, 404 (2010);