产品编号：S688845

产品规格：1g

产品价格：面议

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产品详情

标准品编号:	S688845
名称:	N-Succinimidyl N-Methylcarbamate
别名:	1-[[(Methylamino)carbonyl]oxy]-2,5-pyrrolidinedione; N-[(Methylcarbamoyl)oxy]succinimide; Methylcarbamic Acid Succinimido derivative; 2,5-Dioxopyrrolidin-1-yl methylcarbamate
CAS号:	18342-66-0
分子式:	C₆H₈N₂O₄
外观:	白色至白色固体
熔点:	140-150°C
分子量:	172.14
储存:	Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:	Dichloromethane (Slightly), DMSO (Slightly)
类别:	Building Blocks; Miscellaneous;
应用:	N-Succinimidyl N-Methylcarbamate is used as a reagent in the synthesis of Argifin, a natural product chitinase inhibitor with chemotherapeutic potential. N-Succinimidyl N-Methylcarbamate is also used as a reagent in the preparation of 5-Amino-N1-methyl-1H-imidazole-1,4-dicarboxamide (A616300); a metabolite of Temozolomide (T017775) which is an imidazotetrazine alkylating agent and antineoplastic.
参考文献	Dixon, M.J., et al.: Bioorg. Med. Chem. Lett., 15, 4717 (2005); Newlands, E.S., et al.: Cancer Treat. Rev., 23, 35 (1997); Kim, C., et al.: J. Biol. Chem., 274, 1233 (1999); Hait, W., et al.: Cancer Res., 69, 1263 (2009); Wang, Y., et al.: J. Org. Chem., 62, 7288 (1997)