产品编号：S684100

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	S684100
名称:	SR 3677
别名:	N-[2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benzodioxin-2-carboxamide;
CAS号:	1072959-67-1
分子式:	C₂₂H₂₄N₄O₄
分子量:	408.45
类别:	Research Tools;
应用:	SR 3677 is an ATP-competitive inhibitor of Rho-kinases (ROCK-I/ROCK-II) which reduces amyloid-β production. It’s hypothesized that Alzheimer’s Disease, can be treated with this type of treatment, and delay further progression of the disease.
参考文献	Herskowitz, J. et al.: J. Neurosci., 33, 19086 (2013); Feng, Y. et al.: J. Med. Chem., 51, 6642 (2008);