产品编号：S675615
产品规格：2.5mg
产品价格：面议
| 标准品编号: | S675615 |
| 名称: | Sofosbuvir (R)-Phosphate |
| 别名: | (2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate; N-[[P(R),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-Methylethyl Ester |
| CAS号: | 1190308-01-0 |
| 分子式: | C₂₂H₂₉FN₃O₉P |
| 外观: | 白色至白色固体 |
| 熔点: | 76-82°C |
| 分子量: | 529.45 |
| 储存: | -20°C Freezer |
| 溶解度: | Chloroform (Slightly), DMSO (Slightly), Ethyl Aceatae (Slightly) |
| 类别: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Sofosbuvir (R)-Phosphate is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. |
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