产品编号：S675610
产品规格：50mg
产品价格：面议
| 标准品编号: | S675610 |
| 名称: | Sofosbuvir 5'-Desphosphate 3'-O-[(S)-Phosphate] |
| 别名: | (2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)amino)propanoate |
| 杂质: | 3 |
| CAS号: | 1337482-15-1 |
| 分子式: | C₂₂H₂₉FN₃O₉P |
| 外观: | 未标明外观 |
| 熔点: | 未标明外观 |
| 分子量: | 529.45 |
| 溶解度: | 未标明外观 |
| 类别: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Sofosbuvir 5'-Desphosphate 3'-O-[(S)-Phosphate] is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. |
| 参考文献 | |
