产品编号：S491040

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	S491040
名称:	(R)-Sitagliptin rac-Fumarate Adduct (mixture of diastereomers)
别名:	N-[(1R)-3-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-oxo-1-[(2,4,5-trifluorophenyl)methyl]propyl]-L-Aspartic acid; Sitagliptin Maleate adduct
杂质:	Sitagliptin Tablets EP Impurity FP-A
CAS号:	2088771-60-0
分子式:	C₂₀H₁₉F₆N₅O₅
分子量:	523.39
类别:	Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Sitagliptin Fumarate Adduct is an impurity of Sitagliptin (S491000), a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.
参考文献	Kim, D., et al.: J. Med. Chem. 48, 141 (2005), Ahren, B., et al.: Eur. J. Pharmacol. 521 164 (2005), Bergman, A., et al: Clin. Ther. 28, 55 (2006)