产品编号：S353530

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	S353530
名称:	(2S,3R)-2-((3S,10R,13S)-3-Hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-6-methylheptan-3-yl 4-Nitrobenzoate
分子式:	C₃₄H₄₉NO₅
分子量:	551.76
类别:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(2S,3R)-2-((3S,10R,13S)-3-Hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-6-methylheptan-3-yl 4-Nitrobenzoate is an intermediate in the synthesis of 22α-Hydroxy Cholesterol (H918015). It is a 22R-metabolite of Cholesterol (C432501). 22-Hydroxycholesterol inhibits chemokine receptor activity.
参考文献	Samson, M., et al.: J. Biol. Chem., 272, 24934 (1997), Mackay, C., et al.: Nature Immunol., 2, 95 (2001), Navenot, J., et al.: J. Mol. Biol., 313, 1181 (2001),