产品编号：S253802
产品规格：1mg
产品价格：面议
| 标准品编号: | S253802 |
| 名称: | Selonsertib Isopropyl-d7 |
| 别名: | 5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]benzamide-d7; 5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-yl}benzamide-d7; GS 4977-d7; GS 4997-d7 |
| 参考CAS号: | 1448428-04-3 |
| 分子式: | C₂₄H₁₇D₇FN₇O |
| 分子量: | 452.54 |
| 类别: | Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; |
| 应用: | Selonsertib Isopropyl d7 is an isotope labelled compound of Selonsertib (S253800). Selonsertib is an apoptosis signal-regulating kinase 1 (ASK1) inhibitor with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. Selonsertib interacts with the catalytic kinase domain of ASK1 and prevents its phosphorylation and activation. As a result, the expression of genes involved in fibrosis, cellular proliferation, and apoptosis are down regulated. |
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