产品编号：S143503

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	S143503
名称:	Saxagliptin-15N,D2 Hydrochloride
别名:	(1S,3S,5S)-2-[(2S)-2-Amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile-15N,D2 Hydrochloride; BMS 477118-15N,D2 Hydrochloride; BMS 477118-11-15N,D2 Hydrochloride; Onglyza-15N,D2 Hydrochloride;
CAS号:	1309934-06-2
参考CAS号:	Unlabelled: 361442-04-8
分子式:	C₁₈H₂₄D₂ClN₂¹⁵NO₂
分子量:	354.88
类别:	Research Tools;
应用:	Isotope labelled Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.
参考文献	Feng, J., et al.: J. Med. Chem., 50, 2297 (2007), Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008), Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008),