产品编号：R701700

产品规格：2.5mg

产品价格：面议

---

产品详情

标准品编号:	R701700
名称:	Rupintrivir
别名:	(2E,4S)-4-[[(2R,5S)-2-[(4-Fluorophenyl)methyl]-6-methyl-5-[[(5-methyl-3-isoxazolyl)carbonyl]amino]-1,4-dioxoheptyl]amino]-5-[(3S)-2-oxo-3-pyrrolidinyl]-2-pentenoic Acid; AG 7088;
CAS号:	223537-30-2
分子式:	C₃₁H₃₉FN₄O₇
外观:	白色至白色固体
熔点:	170-171°C
分子量:	598.66
储存:	-20°C Freezer, Under Inert Atmosphere
溶解度:	Chloroform (Slightly), Methanol (Slightly)
类别:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Rupintrivir (formerly AG7088) is an irreversible inhibitor of the human rhinovirus (HRV) 3C protease that has been demonstrated to have in vitro activity against all HRVs tested, consistent with its interaction with a strictly conserved subset of amino acids in the 3C protease.
参考文献	Arruda, E., et al.: J. Clin. Microbiol., 35, 2864 ( 1997), Dragovich, P., et al.: J. Med. Chem., 42, 1213 (1999), Kaiser, L., et al.: Antivir. Res., 47, 215 (2000), Binford, S., et al.: Antimicrob. Agents Chemother., 49, 619 (2005), Schmidtke, M., et al.: J. Antimicrob. Chemother., 56, 648 (2005), Arden, K., et al.: J. Med. Virol., 78, 1232 (2006),