产品编号：R143335
产品规格：1mg
产品价格：面议
| 标准品编号: | R143335 |
| 名称: | Regorafenib N-β-D-Glucuronide Methyl Ester |
| 别名: | (2S,3S,4S,5R,6R)-Methyl 6-(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)ureido)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate |
| 分子式: | C₂₈H₂₅ClF₄N₄O₉ |
| 外观: | 白色固体 |
| 分子量: | 672.97 |
| 类别: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; Carbohydrates and Oligosaccharides; |
| 应用: | Regorafenib N-β-D-Glucuronide Methyl Ester is an intermediate in the synthesis of Regorafenib N-β-D-Glucuronide Sodium Salt (R143320), which is a derivative of Regorafenib (R143000); a compound that inhibits PDGFR tyrosine kinase with IC50=83nM. Also useful for the treatment of inflammation and as an anti-proliferative agent. |
| 参考文献 | |
