产品编号：Q550630

产品规格：

产品价格：面议

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产品详情

标准品编号:	Q550630
名称:	2-((S)-Quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinoline
CAS号:	1796933-62-4
分子式:	C₁₉H₂₆N₂
外观:	Yellow Solid
分子量:	282.42
储存:	冰箱
溶解度:	Methanol
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	2-((S)-Quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinoline is an intermediate in the sythesis of (S,S)-Palonosetron Acid which is an impurity in the synthesis of (S,S) Palonosetron (P165800), serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.
参考文献	Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),