产品编号：P688250
产品规格：5mg
产品价格：面议
| 标准品编号: | P688250 |
| 名称: | Ponatinib |
| 别名: | 3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]benzamide; AP 24534; Iclusig |
| CAS号: | 943319-70-8 |
| 分子式: | C₂₉H₂₇F₃N₆O |
| 外观: | 白色至Pale Beige Solid |
| 熔点: | >175°C (dec.) |
| 分子量: | 532.56 |
| 储存: | Amber Vial, 冰箱, Under inert atmosphere |
| 溶解度: | DMSO (Slightly), Methanol (Slightly) |
| 类别: | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Ponatinib is a tyrosine kinase inhibitors (TKI) and used to treat chronic myeloid leukemia (CML) (1,2,3). Ponatinib is also used in combination with other drugs, such as forskolin, to combat TKI resistance in patient with CML (3), targeted drug in small-cell lung cancer. Potent FAK inhibitor. FGFR/VEGFR/Bcr-Abl inhibitor |
| 参考文献 | |
