产品编号：P688215

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	P688215
名称:	Pomalidomide M16
别名:	4-Amino-2-(2,6-dioxopiperidin-3-yl)-7-hydroxyisoindoline-1,3-dione
CAS号:	1547162-46-8
分子式:	C₁₃H₁₁N₃O₅
分子量:	289.24
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Pomalidomide M16 is a derivative of Pomalidomide (P688200), an amino derivative of Thalidomide (T338850), which is a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma.
参考文献	Ruchelman, A. et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013); Latif, T. et al.: Exp. Hematol. Oncol., 1, 27 (2012); Man, H. et al.: Bioorg. Med. Chem. Lett., 13, 3415 (2003); Muller, G. et al.: Bioorg. Med. Chem. Lett., 9, 1625 (1999);Gupta, D., et. al.: Leuk., 15, 1950 (2001);Lokhorst, H., et. al.: N. Engl. J. Med., 373, 1207 (2015)