产品编号：P702120

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	P702120
名称:	(4S)-4-Hydroxy Pravastatin Lactone
别名:	(2S)-(1S,3S,7S,8S,8aR)-3-Hydroxy-8-(2-((4S)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2-methylbutanoate
分子式:	C₂₃H₃₄O₆
分子量:	406.51
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(4S)-4-Hydroxy Pravastatin Lactone is an intermediate in the synthesis of Pravastatin 6'-Ketone Sodium Salt (P702050), which is an impurity of Pravastatin Sodium (P702000), which is a competitive inhibitor of HMG-CoA reductase. It can be used as a drug to for lowering cholesterol and preventing cardiovascular disease.
参考文献	Serizawa, N., et al.: J. Antibiot., 36, 604 (1983), Yoshino, G., et al.: Lancet, 2, 740 (1986), White, H.D, et al.: N. Engl. J. Med., 343, 317 (2000);