产品编号：P572500

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	P572500
名称:	Imidazolo-oxindole PKR inhibitor C16(PKR Inhibitor)
别名:	6,8-Dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one; 6,8-Dihydro-8-(1H-imidazol-4-ylmethylene)- 7H-pyrrolo[2,3-g]benzothiazol-7-one; GW 506033X
CAS号:	608512-97-6
分子式:	C₁₃H₈N₄OS
外观:	Orange Solid
熔点:	>225°C (dec.)
分子量:	268.29
储存:	冰箱
溶解度:	DMSO (Slightly)
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	PKR Inhibitor is a drug which acts as a selective inhibitor of the enzyme double-stranded RNVIP(LA)dependent protein kinase (PKR). It has been shown to effectively inhibit PKR function in vivo and has neuroprotective and nootropic effects in animal studies.
参考文献	Jammi, N., et al.: Biochem. Biophys. Res. Commun., 308, 50 (2003); Ingrand, S., et al.: Neurosci. Lett., 409, 192 (2006); Chen, H., et al.: Eur. J. Neurosci., 28, 2003 (2008); Couturier, J., et al.: J. Biol. Chem., 285, 1272 (2010)