产品编号：P480600

产品规格：5g

产品价格：面议

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产品详情

标准品编号:	P480600
名称:	3-(1-Piperazinyl)-1,2-benzisothiazole
别名:	3-(Piperazin-1-yl)benzoisothiazole; N-(3-Benzisothiazolyl)piperazine; 1-(1,2-Benzisothiazol-3-yl)piperazine; Ziprasidone EP Impurity A;
杂质:	Ziprasidone EP Impurity A
CAS号:	87691-87-0
分子式:	C₁₁H₁₃N₃S
外观:	Pale Yellow to Yellow Solid
熔点:	90 - 92°C
分子量:	219.31
储存:	冰箱
溶解度:	DMSO (Slightly), Methanol (Slightly)
类别:	Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	3-(1-Piperazinyl)-1,2-benzisothiazole (Ziprasidone EP Impurity A) is a reagent used to synthesize Ziprasidone (Z485000, HCl salt, monohydrate), a combined serotonin (5HT2) and dopamine (D2) receptor antagonist.
参考文献	Prakash, C., et al.: Brit. J. Clin. Pharmacol., 49, 35S (2000); Orjales, A., et al.: J. Med. Chem., 46, 5512 (2003); Graham, J., et al.: Bioorg. Med. Chem. Lett., 18, 489 (2008); Bench, C.J., et al.: Psychopharmacology, 112, 308 (1993), Goldstein, J.M.: Exp. Opin. Invest. Drugs, 4, 291 (1995)