产品编号：P319330

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	P319330
名称:	2-Phenyl α-Cortolone 1,3-Dioxane
别名:	(4’R,5R,5’R,8S,9S,10S,13S,14S)-3,5’-Dihydroxy-10,13-dimethyl-2’-phenyltetradecahydrospiro[cyclopenta[a]phenanthrene-17,4’-[1,3]dioxan]-11(2H)-one;
分子式:	C₂₈H₃₈O₅
外观:	White Powder
分子量:	454.6
溶解度:	Dichloromethane; Methanol
类别:	Standards; Controlled Substances and Drugs of Abuse for Forensic Testing; Steroids;
应用:	2-Phenyl α-Cortolone 1,3-Dioxane is an intermediate used in the synthesis of α-Cortolone (C696280), which is a human urinary metabolite of Cortisol ((H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.
参考文献	Yergey, A.L., et. al.: Steroids, 60, 295 (1995); Vigore, L., et al.: Cancer Ther., 6, 699 (2008); Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009); Lemos, D., et al.: J. Endocrinol., 201, 275 (2009); Chen, S., et al.: Am. J. Physiol., 296 (2009)