产品编号：P293950

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	P293950
名称:	PF-573228
别名:	3,4-Dihydro-6-[[4-[[[3-(methylsulfonyl)phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2(1H)-quinolinone; 6-[(4-((3-(Methanesulfonyl)benzyl)amino)-5-trifluoromethylpyrimidin-2-yl)amino]-3,4-dihydro-1H-quinolin-2-one; PF 573228;
CAS号:	869288-64-2
分子式:	C₂₂H₂₀F₃N₅O₃S
外观:	白色固体
熔点:	>242°C (dec.)
分子量:	491.49
储存:	冰箱
溶解度:	DMSO, Methanol (Sparingly)
类别:	Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	A novel focal adhesion kinase inhibitor that has been shown to suppress the adverse phenotype of endocrine-resistant breast cancer cells and improve endocrine response in endocrine-sensitive cells.
参考文献	Slack-Davis, J.K. et al.: J. Biol. Chem., 282, 14845 (2007); Hiscox, S. et al.: Breast Cancer Res. Treat., 125, 659 (2011);