产品编号：P206500
产品规格：5mg
产品价格：面议
| 标准品编号: | P206500 |
| 名称: | Patulin |
| 别名: | 4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one; Clairformin; Clavacin; Clavatin; Claviformin; DL-Patulin; Expansin; Expansine; Mycoin; Mycoin C; Mycoin C3; NSC 32951; NSC 8120; Patuline; Penicidin; Terinin; |
| CAS号: | 149-29-1 |
| 分子式: | C₇H₆O₄ |
| 外观: | 白色至Pale Orange Solid |
| 熔点: | 103-107°C |
| 分子量: | 154.12 |
| 储存: | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| 溶解度: | Acetone (Slightly), Methanol (Slightly, Heated) |
| 类别: | Standards; Others; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics; |
| 应用: | Patulin (PAT), a mycotoxin produced by certain species of Penicillium, Aspergillus, and Byssochlamys, is mainly found in ripe apple and apple products. Patulin-induced genotoxicity and modulation of glutathione in Hep G2 cells. Patulin is an antibiotic. Patulin-induced nephropathy and gastrointestinal tract malfunction have been demonstrated in several animal models. The oral LD50 value of patulin ranges between 29 and 55 mg/kg body weight in rodents and 170 mg/kg body weight in poultry. The World Health Organization considers patulin cytotoxic and established a safety level of patulin in apple juice at 50 μM. At 100-200 μM, patulin can directly increase intracellular oxidative stress in HEK293 and HL-60 cells. In 1944, this compound was tested in a clinical trial for potential antibioti |
| 危险品: | Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package |
| 参考文献 | |
