产品编号：P173502

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	P173502
名称:	Pamoic Acid-d10
别名:	4,4'-Methylenebis[3-hydroxy-2-naphthalenecarboxylic Acid; 2,2'-Dihydroxy-1,1'-dinaphthylmethane-3,3'-dicarboxylic Acid; 4,4'-Methylenebis[3-hydroxy-2-naphthoic Acid]; Embonic Acid; KG 122; NSC 30188; NSC 40132;
CAS号:	1215327-33-5
参考CAS号:	130-85-8-unlabelled
分子式:	C₂₃H₆D₁₀O₆
分子量:	398.43
类别:	Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Labelled Pamoic Acid. Agonist of the orphan G protein-coupled receptor GPR35: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity. Used as an inhibitor in the real-time fluorescence enzymatic characterization study of specialized human DNA polymerases. Enzyme replacement therapy in pancreatic enzyme deficiency.
参考文献	Fonge H., et al.: Bioconjugate Chem., 18, 1924 (2007), Mayr, G.W., et al.: J. Biol. Chem., 282, 35424 (2007); Zhao, P. et al.: Mol. Pharmacol., 78, 560 (2010); Dorjsujen, D. et al.: Nuc. Acids Res., 37, e128 (2009);