产品编号：P165820

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	P165820
名称:	Palonosetron-3-ene N-Oxide
别名:	2,4,5,6-Tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-1H-benz[de]isoquinolin-1-one
CAS号:	1021456-82-5
分子式:	C₁₉H₂₂N₂O₂
外观:	白色至淡黄色固体
熔点:	>58°C (dec.)
分子量:	310.39
储存:	Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:	Methanol (Slightly), Water (Slightly)
类别:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Palonosetron-3-ene N-Oxide is an impurity of Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.
参考文献	Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993); Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995); Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003); Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004); Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004)

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