产品编号：P165810

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	P165810
名称:	(S,R)-Palonosetron Hydrochloride Contains up to ~35% (R,R)-isomer
别名:	(3aS)-2-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one Hydrochloride; RS 25233-197;
CAS号:	135729-76-9
参考CAS号:	Free base: 149654-00-2
分子式:	C₁₉H₂₅ClN₂O
外观:	Pale Yellow to Light Orange Solid
熔点:	>45°C (dec.)
分子量:	332.87
储存:	Hygroscopic, 冰箱, under inert atmosphere
溶解度:	DMSO (Slightly), Methanol (Slightly), Water (Slightly)
类别:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	The (S,R)-enantiomer of Palonosetron (P165800), a potent and selective antagonist, with 5-HT3 receptor in vitro. An impurity of Palonosetron.
参考文献	Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),

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