产品编号：P165800

产品规格：1g

产品价格：面议

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产品详情

标准品编号:	P165800
名称:	(S,S)-Palonosetron Hydrochloride
别名:	(3aS)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one Hydrochloride; Aloxi; Onicit; RS-25259-197
CAS号:	135729-62-3
参考CAS号:	Free cmpd: 135729-61-2
分子式:	C₁₉H₂₄N₂O • (HCl)
外观:	白色至白色固体
熔点:	238 - 244°C
分子量:	296.413646
储存:	冰箱
溶解度:	Methanol (Slightly, Heated), Water (Slightly)
类别:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(S,S)-Palonosetron Hydrochloride is a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.
参考文献	Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),

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