产品编号：P132007

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	P132007
名称:	p-Hydroxy-PAC-1-d8
别名:	(E)-N'-(3-Allyl-2-hydroxybenzylidene)-2-(4-(4-hydroxybenzyl)piperazin-1-yl)acetohydrazide-d8
分子式:	C₂₃H₂₀D₈N₄O₃
分子量:	416.54
类别:	Standards; Isotopic Labeled Analogues;
应用:	p-Hydroxy-PAC-1-d8 is deuterium labeled p-Hydroxy PAC-1 (P132005). p-Hydroxy PAC-1 isa metabolite of PAC-1 (P132000),which is a potential anti-tumor drug candidate that activates caspase 3 and induces apoptosis in both in vitro and in vivo against mice tumors. Metabolites andderivatives of PAC-1 are useful compounds to investigate the mechanism of action and toserve as standards(ie. LC/MS).
参考文献	Ren, L., et al.:ÂJ. Chromatogr. B (2008);ÂSlee, E., et al.: J. Biol. Chem., 276, 7320 (2001); Pop, C., et al.: Biochemistry, 42, 12311 (2003); Li, L., et al.: Science, 305, 1471 (2004); Green, D., et al.: J. Clin. Invest., 115, 2610 (2005); Satoh, T., et al.: Clin. Cancer Res., 15, 3872 (2009)