产品编号：O847390

产品规格：500mg

产品价格：面议

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产品详情

标准品编号:	O847390
名称:	8-Oxo-Benzylguanine
别名:	2-Amino-7,9-dihydro-6-(phenylmethoxy)-8H-purin-8-one; NU 6043
CAS号:	158754-46-2
分子式:	C₁₂H₁₁N₅O₂
外观:	Pale Brown Solid
熔点:	243-248°C (dec.)
分子量:	257.25
储存:	Hygroscopic, 冰箱, Under Inert Atmosphere
溶解度:	DMSO (Slightly), Methanol (Slightly)
类别:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	8-Oxo-Benzylguanine is a derivative of O-Benzylguanine, an reversible inhibitor of the mammalian DNA repair protein, O6-alkylguanine-DNA alkyltransferase. O-Benzylguanine is known to assists in the protection against carcinogenic and therapeutic alkylating agents.
参考文献	Dolan, M.E., et al.: Proc. Natl. Acad. Sci. USA, 87, 5356 (1990), Goodtzova, K., et al.: Biochemistry, 33, 385 (1994), Elder, R.H., et al.: Biochem. J., 298, 231 (1994)

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