产品编号：O712950

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	O712950
名称:	OTS514
别名:	9-[4-[(1R)-2-Amino-1-methylethyl]phenyl]-8-hydroxy-6-methylthieno[2,3-c]quinolin-4(5H)-one; (R)-9-[4-(1-Aminopropan-2-yl)phenyl]-8-hydroxy-6-methylthieno[2,3-c]quinolin-4(5H)-one
CAS号:	1338540-63-8
分子式:	C₂₁H₂₀N₂O₂S
分子量:	364.46
类别:	Standards; Enzyme Activators and Inhibitors;
应用:	OTS514 is a potent T-lymphokine-activated killer cell-originated protein kinase (TOPK) inhibitor. TOPK is involved with cancer cell proliferation and cancer stem cell maintenance. OTS514 also downregulates the oncogenic transcriptional factor, forkhead box protein M1 (FOXM1).
参考文献	Ikeda, Y., et al.: Clin Cancer Res. 22, 6110 (2016); Kato, T., et al.: Oncotarget. 7, 17652 (2016)