产品编号：N900302

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	N900302
名称:	NSC-33994-d4
别名:	4,4'-[(1E)-1,2-Diethyl-1,2-ethenediyl]bis[2-[(diethylamino)methyl]phenol-d4; (E)-4,4'-(1,2-Diethyl-1,2-ethenediyl)bis[2-[(diethylamino)methyl]phenol-d4;
CAS号:	1795134-33-6
参考CAS号:	82058-16-0-unlabelled
分子式:	C₂₈H₃₈D₄N₂O₂
分子量:	442.67
类别:	Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Labelled NSC-33994 (N900300). NSC-33994 is novel inhibitor of JAK2 tyrosine kinase (Janus kinase 2 ). Janus kinase 2 (JAK2) plays a crucial role in the pathomechanism of myeloproliferative disorders and hematological malignancies.
参考文献	Tanner, J., et al.: J. Biol. Chem., 270, 6523 (1995), Rane, S., et al.: Oncogene, 19, 5662 (2000, Verma, A., et al.: Cancer Metastasis Rev., 22, 423 (2003), Levine, R., et al.: Cancer Cell., 7, 387 (2005), Kiss, et al.: Bioorg. Med. Chem. Lett., 19, 3598 (2009),