产品编号：N900250

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	N900250
名称:	NS 3623
别名:	1-(3-Trifluoromethylphenyl)-3-[2-(1H-tetrazol-5-yl)-4-bromophenyl]urea; N-[4-Bromo-2-(2H-tetrazol-5-yl)phenyl]-N'-[3-(trifluoromethyl)phenyl]-urea
CAS号:	343630-41-1
分子式:	C₁₅H₁₀BrF₃N₆O
分子量:	427.18
类别:	Research Tools;
应用:	NS 3623 selectively activates the human ether-a-go-go related gene (hERG) potassium channel which mediates the repolarizing cardiac current IKr. NS 3623 an IKr agonist, cause QT interval prolongation, increasing the risk of dangerous ventricular fibrillations, eventually leading to sudden cardiac death.
参考文献	Hansen, R. et al.: J. Cardiovas. Pharmacol., 52, 35 (2008)