产品编号：N757002

产品规格：1mg

产品价格：面议

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产品详情

标准品编号:	N757002
名称:	(R,S)-Nornicotine-13C6
别名:	3-(2-Pyrrolidinyl)pyridine-13C6; (±)-1'-Demethylnicotine-13C6; (±)-3-(2-Pyrrolidinyl)pyridine-13C6; (±)-1'-Demethylnicotine-13C6; (±)-Nornicotine-13C6; 2-(3-Pyridinyl)pyrrolidine-13C6; 3-(Pyrrolidin-2-yl)pyridine-13C6;
参考CAS号:	Unlabelled: 5746-86-1
分子式:	C₃¹³C₆H₁₂N₂
外观:	Clear Dark Yellow Oil
熔点:	N/A
分子量:	154.16
储存:	Amber Vial, -20°C Freezer, Under inert atmosphere
溶解度:	Chloroform (Slightly), Methanol (Slightly)
类别:	Standards; Isotopic Labeled Analogues; Environmental Standards, Mutagens and Metabolites; Nicotine Derivatives and Metabolites;
应用:	(RS)-Nornicotine-13C6 is an isotope labelled analog of (RS)-Nornicotine (N757000), a tobacco alkaloid and the major Nicotine (N412420) metabolite in brain. Nornicotine appears to activate different nAChR subtypes, has a better pharmacokinetic profile, and produces less toxicity than Nicotine. Nornicotine shows a significant analgesic activity.
参考文献	Hecht, S., et al.: Carcinogenesis, 9, 875 (1988), Rivenson, A., et al.: Cancer Res., 48, 6912 (1988), Hoffmann, D., et al.: Chem. Res. Toxicol., 14, 767 (2001), Kool, J., et al.: J. Med. Chem., 49, 3287 (2006), Kool, J., et al.: Drug Metab. Dispos., 35, 640 (2007),