产品编号：N565527

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	N565527
名称:	4-Nitrothalidomide-d2
别名:	2-(2,6-Dioxo-3-piperidinyl)-4-nitro-1H-isoindole-1,3(2H)-dione-d2;2-(2,6-Dioxopiperidin-3-yl)-4-nitro-isoindole-1,3-dione-d2;2-(2,6-Dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione-d2;4-Nitro-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
参考CAS号:	19171-18-7
分子式:	C₁₃H₇D₂N₃O₆
外观:	Pale-Yellow Solid
分子量:	305.24
溶解度:	DMF; Methanol; Acetonitrile
种类:	Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	4-Nitrothalidomide-d2 is an intermediate for the synthesis of Pomalidomide-(d4 major) (P688202), which is the labeled analogue of Pomalidomide (P688200), a thalidomide derivative, a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma.
参考文献	Ruchelman, A. et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013); Latif, T. et al.: Exp. Hematol. Oncol., 1, 27 (2012); Man, H. et al.: Bioorg. Med. Chem. Lett., 13, 3415 (2003); Muller, G. et al.: Bioorg. Med. Chem. Lett., 9, 1625 (1999)