产品编号：N544955

产品规格：250mg

产品价格：面议

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产品详情

标准品编号:	N544955
名称:	Nitro-pyrazolone
别名:	1-(3,4-Dimethylphenyl)-3-methyl-4-nitro-1H-pyrazol-5-ol;
分子式:	C₁₂H₁₃N₃O₃
外观:	Yellow Solid
分子量:	247.25
储存:	-20°C Freezer
溶解度:	Tetrahydrofuran; Chloroform; Methanol;
种类:	Building Blocks; Miscellaneous;
应用:	Nitro-pyrazolone is an intermediate used in the synthesis of N-Hydroxy Eltrombopag (H825795), which is a derivative compound of Eltrombopag (508000), an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.
参考文献	Bussel, J., et al.: New Eng. J. Med., 357, 2237 (2007), Marsilje, T., et al.: Bioorg. Med. Chem. Lett., 18, 5259 (2008), Alper, P., et al.: Bioorg. Med. Chem. Lett., 18, 5255 (2008),