产品编号：N407767

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	N407767
名称:	β-Nicotinamide Mononucleotide-13C5
别名:	3-(Aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)pyridinium-13C5 Inner Salt;3-Carbamoyl-1-β-D-ribofuranosylpyridinium Hydroxide 5'-Phosphate-13C5 Inner Salt; NMN-13C5; Nicotinamide Mononucleotide-13C5; Nicotinamide Ribonucleoside 5'-Phosphate-13C5; Nicotinamide Ribonucleotide-13C5; Nicotinamide Ribotide-13C5; β-D-NMN-13C5; β-NMN-13C5;
参考CAS号:	类似: 1094-61-7
分子式:	C₆¹³C₅H₁₅N₂O₈P
分子量:	339.18
种类:	Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites; Nicotine Derivatives and Metabolites;
应用:	The labelled analogue of a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.
参考文献	Yoshino, J. et al.: Cell Metab., 14, 528 (2011); Caton, P.W. et al.: Diabetologia, 54, 3083 (2011); Formentini, L. et al.: BIochem. Pharmacol., 77, 1612 (2009);