产品编号：N389655

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	N389655
名称:	Nelotanserin
别名:	N-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-N'-(2,4-difluorophenyl)urea; 1-(2,4-Difluorophenyl)-3-[4-methoxy-3-(4-bromo-1-methyl-1H-pyrazol-5-yl)phenyl]urea; 1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea; APD 125;
CAS号:	839713-36-9
分子式:	C₁₈H₁₅BrF₂N₄O₂
分子量:	437.24
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Nelotanserin is a potent selective 5-HT2A inverse agonist, nelotanserin has low nanomolar potency on the 5-HT2A receptor with at least 30- and 5000-fold selectivity compared with 5-HT2C and 5-HT2B receptors.
参考文献	Al-Shamma, H.A., et al.: J Pharmacol Exp Ther., 332, 281-90 (2010); Teegarden, B.R., et al.: J Med Chem., 53, 1923-36 (2010);