产品编号：N378808

产品规格：10mg

产品价格：面议

---

产品详情

标准品编号:	N378808
名称:	Naxagolide-3-oxo O-Methyl
别名:	(4aR,10bR)-4a,5,6,10b-Tetrahydro-9-methoxy-4-propyl-2H-naphth[1,2-b]-1,4-oxazin-3(4H)-one; (4aR-trans)- 4a,5,6,10b-Tetrahydro-9-methoxy-4-propyl-2H-naphth[1,2-b]-1,4-oxazin-3(4H)-one
CAS号:	88058-74-6
分子式:	C₁₆H₂₁NO₃
外观:	白色固体
分子量:	275.34
溶解度:	Dichloromethane, DMSO, Ethyl Acetate, Methanol
种类:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Naxagolide-3-oxo O-Methyl is an intermediate in the synthesis of Naxagolide Hydrochloride (N379800), which is a dopamine D2-receptor agonist. Used for treatment of extrapyramidal disorders. Antiparkinsonian drug.
参考文献	Fujita, N., et al.: Brain Res., 333, 231 (1985); Weiss, F., et al.: Eur. J, Pharmacol., 337, 219 (1997); Wilson, A., et al.: J. Med. Chem., 48, 4153 (2005); Ginovart, N., et al.: J. Neurochem., 97, 1089 (2006); Willeit, M., et al.: Biol. Psychiatry, 59, 389 (2006)