产品编号：N378805

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	N378805
名称:	Naxagolide-O-methyl Hydrochloride
别名:	(4aR-trans)-3,4,4a,5,6,10b-Hexahydro-9-methoxy-4-propyl-2H-naphth[1,2-b]-1,4-oxazine Hydrochloride
CAS号:	88058-72-4
参考CAS号:	Free Base: 88058-98-4
分子式:	C₁₆H₂₃NO₂ • HCl
外观:	Light Pink Solid
分子量:	261.363646
储存:	Room Temperature
溶解度:	Dichloromethane, DMSO, Ethyl Acetate, Methanol
种类:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Naxagolide-O-methyl Hydrochloride is an intermediate in the synthesis of Naxagolide Hydrochloride (N379800), which is a dopamine D2-receptor agonist. Used for treatment of extrapyramidal disorders. Antiparkinsonian drug.
参考文献	Fujita, N., et al.: Brain Res., 333, 231 (1985); Weiss, F., et al.: Eur. J, Pharmacol., 337, 219 (1997); Wilson, A., et al.: J. Med. Chem., 48, 4153 (2005); Ginovart, N., et al.: J. Neurochem., 97, 1089 (2006); Willeit, M., et al.: Biol. Psychiatry, 59, 389 (2006)