产品编号：M725125

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	M725125
名称:	3-(Morpholinyl)-N-(4-nitrophenyl)-5,6-dihydropyridin-2-one
别名:	3-(4-Morpholinyl)-1-(4-nitrophenyl)-5,6-dihydro-2(1H)-pyridinone; 5,6-Dihydro-3-(4-morpholinyl)-1-(4-nitrophenyl)-2(1H)-pyridinone;
CAS号:	503615-03-0
分子式:	C₁₅H₁₇N₃O₄
外观:	淡黄色固体
熔点:	164 - 166°C
分子量:	303.31
储存:	冰箱
溶解度:	Chloroform (Slightly), Methanol (Slightly, Heated)
种类:	Standards; Enzyme Activators and Inhibitors;
应用:	3-(Morpholinyl)-N-(4-nitrophenyl)-5,6-dihydropyridin-2-one is a reagent in the synthesis of 4,5-dehydro Apixaban (D229385) an impurity of Apixaban (A726700), a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation
参考文献	Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011)