产品编号：M687545

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	M687545
名称:	Carfilzomib (2R,4S)-2-Hydroxy Acetate
别名:	(αS)-α-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S,3R)-4-(acetyloxy)-3-hydroxy-3-methyl-1-(2-methylpropyl)-2-oxobutyl]-L-phenylalaninamide
CAS号:	1541171-69-0
分子式:	C₄₂H₆₁N₅O₉
外观:	白色固体
分子量:	779.96
储存:	-20°C Freezer
溶解度:	Chloroform; Methanol; Acetonitrile; DMSO
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Carfilzomib (2R,4S)-2-Hydroxy Acetate is an intermediate for the synthesis of Carfilzomib (2R,4S)-Diol (C183470), which is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
参考文献	Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);