产品编号：M493125

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	M493125
名称:	10-Methoxy-10-deacetylbaccatin III
别名:	(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-4,9,11-trihydroxy-6-methoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate
分子式:	C₃₀H₃₈O₁₀
分子量:	558.62
种类:	Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Semi-Synthetic;
应用:	10-Methoxy-10-deacetylbaccatin III is an impurity of Cabazitaxel (C046500), a novel semi-synthetic taxane with antitumor activity used for the treatment of castration-resistant prostate cancer. A microtubule inhibitor.
参考文献	Agarwal, N. et al.: Fut. Oncol., 7, 15 (2011); Mita, A. et al.: Clin. Cancer Res., 15, 723 (2009); Figg, W.D. et al.: Cancer Biol. Ther., 10, 1233 (2010);