产品编号：M425015

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	M425015
名称:	MK-0822
别名:	N-(1-cyanocyclopropyl)-4-fluoro-N2-{(1S)-2,2,2-trifluoro-1-[4'-(methylsulfonyl)biphenyl-4-yl]ethyl}-L-leucinamide, Odanacatib
CAS号:	603139-19-1
分子式:	C₂₅H₂₇F₄N₃O₃S
外观:	白色至白色固体
熔点:	>170°C (dec.)
分子量:	525.56
储存:	Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:	Chloroform (Slightly, Heated, Sonicated), Methanol (Slightly, Sonicated)
种类:	Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	MK-0822 is a newly developed bone-targeting dual action pro-drug for osteoporosis and bone metastasis. It is also an inhibitor of cathepsin K, an enzyme involved in bone resorption.
参考文献	Arns, S., et al.: Bioorg. Medn. Chem., 20, 2131 (2012); Cusick, T., et al., J. Bone. Mineral. Rsch., 27, 524 (2013);