产品编号：M368700

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	M368700
名称:	Misonidazole
别名:	α-(Methoxymethyl)-2-nitro-1H-imidazole-1-ethanol; α-(Methoxymethyl)-2-nitroimidazole-1-ethanol; 1-(2-Hydroxy-3-methoxypropyl)-2-nitroimidazole; 1-(2-Nitro-1-imidazolyl)-3-methoxy-2-propanol; 2-Nitro-1H-imidazole-1-(3-methoxy-2-propanol); NSC 261037; Racemic Misonidazole; Ro 7-0582; SR 1354; SRI 1354
CAS号:	13551-87-6
分子式:	C₇H₁₁N₃O₄
外观:	Yellow to Orange Solid
熔点:	107-109°C
分子量:	201.18
储存:	冰箱
溶解度:	Chloroform (Slightly), Methanol (Slightly)
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Misonidazole can be used as a potential hypoxic cancer cell radiosensitizer and DNA binding and nicking agent. The metabolites of misonidazole can themselves be cytotoxic or they can increase the chemosensitivity and radiosensitivity of the target cells
参考文献	Bonnet, M., et al.: Bioorg. Med. Chem., 22, 2123 (2014); Edwards, D.I.: Comprehensive Med. Chem., 2, 725 (1990); Murata, R., et al.: Radiother. Oncol., 87, 331 (2008); Brown, J.M. The mechanisms of cytotoxicity and chemosensitization by misonidazole and other nitroimidazoles. Int.J.Radiat.Oncol.Biol.Phys. 8(3-4), 675-682 (1982).