产品编号：M364950

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	M364950
名称:	Mirodenafil Dihydrochloride
别名:	5-Ethyl-3,5-dihydro-2-[5-[[4-(2-hydroxyethyl)-1-piperazinyl]sulfonyl]-2-propoxyphenyl]-7-propyl-4H-pyrrolo[3,2-d]pyrimidin-4-one Hydrochloride; 4-[[3-(5-Ethyl-4,5-dihydro-4-oxo-7-propyl-1H-pyrrolo[3,2-d]pyrimidin-2-yl)-4-propoxyphenyl]sulfonyl]-1-piperazineethanol Dihydrochloride; SK 3530;
CAS号:	862189-96-6
参考CAS号:	free base: 862189-95-5
分子式:	C₂₆H₃₉Cl₂N₅O₅S
分子量:	604.59
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Mirodenafil, a phosphodiesterase 5 inhibitor reported to be effective in the treatment of erectile dysfunction, is metabolized by cytochrome P 450 (CYP) 3A4 to the active metabolite N-dehydroxyethyl mirodenafil. Mirodenafil may have drug-drug interactions with ketoconazole and/or rifampicin.
参考文献	Matheny, C., et al.: Drug Metab. Dispos., 32, 1008 (2004), Gupta, M., et al.: J. Clin. Pharmacol., 45, 987 (2005), Ek, M., et al.: Biochem. Pharmacol., 74, 496 (2007), Lee, H., et al.: Xenobiotica, 38, 21 (2008),

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