产品编号：M332848

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	M332848
名称:	Methyl 4-Amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylate
CAS号:	182808-04-4
分子式:	C₁₀H₁₀ClNO₃
分子量:	277.64
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Methyl 4-Amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylate is an impurity of Prucalopride (P838950), a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe. In addition, it is an intermediate in the preparation of enterokinetic agent R108512.
参考文献	Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008), McKinnell, R., et al.: J. Med. Chem., 52, 5330 (2009), Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008); Willemsens, B. et al.: ACS Symp. Ser., 870, 125 (2004);