产品编号：M330720

产品规格：250mg

产品价格：面议

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产品详情

标准品编号:	M330720
名称:	6-Methylthioguanine
别名:	6-(Methylthio)-1H-purin-2-amine; 2-Amino-6-methylmercaptopurine; NSC 29420; 2-Amino-6-methylthiopurine; S-Methyl-6-thioguanine; S6-Methyl-6-thioguanine;
CAS号:	1198-47-6
分子式:	C₆H₇N₅S
外观:	白色至白色固体
熔点:	228-230°C
分子量:	181.22
储存:	-20°C Freezer
溶解度:	DMSO (Slightly), Methanol (Slightly)
种类:	Standards; Environmental Standards, Mutagens and Metabolites;
应用:	A metabolite of 2’-Deoxy-6-thio Guanosine (D281650) and 6-Thioguanine. An effective immunosuppressant and anticancer agent, however chronic exposure can be mutagenic in human cells as long-term use of thiopurines was found to be associated with a significantly increased risk of various types of cancer.
参考文献	Loo, T.L. et al.: Cancer Chemother. Pharmacol., 6, 131 (1981); Yuan, B. et al.: ACS Chem. Biol., 5, 1021 (2010); Kroplin, T. et al.: Adv. Exp. Med. Biol., 431, 741 (1998);