产品编号：M330083

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	M330083
名称:	N-​[(1R)​-​1-​[(Methoxymethylamino​)​carbonyl]​-​3-​methylbutyl]​-carbamic Acid 1,​1-​Dimethylethyl Ester
别名:	(R)-[1-[(Methoxymethylamino)carbonyl]-3-methylbutyl]-carbamic Acid 1,1-Dimethylethyl Ester; [(1R)-1-[(Methoxymethylamino)carbonyl]-3-methylbutyl]-carbamic Acid 1,1-Dimethylethyl Ester
CAS号:	129603-01-6
分子式:	C₁₃H₂₆N₂O₄
外观:	Clear Colorless Oil
分子量:	274.36
储存:	冰箱
溶解度:	DMSO (Slightly), Methanol (Slightly)
种类:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N-​[(1R)​-​1-​[(Methoxymethylamino​)​carbonyl]​-​3-​methylbutyl]​-carbamic Acid 1,​1-​Dimethylethyl Ester is an intermediate in synthesizing (R)-2-Amino-4-methyl-1-((S)-2-methyloxiran-2-yl)pentan-1-one Trifluoroacetate Salt (A605100), an impurity of carfilzomib (C183460). Carfilzomib is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
参考文献	Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012)